Blood And Protein in urine and Chronic Kidney Disease Progression

Hematuresis and Protein in urine are the common symptoms in CKD. Do you know these symptoms can predicts the CKD Progression.The following content will show you the knowledge about this.

measuring a small protein in the blood and urine can predict which patients with non-advanced chronic kidney disease (CKD) will progress to a more serious form of the disease, according to a new study. The findings could be used to devise a new screening method for identifying which patients should receive aggressive therapies to prevent the progression of their disease.
The blood and urine of some individuals with impaired kidney function have increased levels of a small protein called Neutrophil Gelatinase-Associated Lipocalin (NGAL). NGAL is released from injured renal tubular cells, which are cells crucial for proper functioning of the kidneys. Preliminary research has also shown that individuals with high levels of NGAL experience worsening of their kidney function within one year, compared with individuals with lower levels of NGAL. However, no definitive study has demonstrated the potential of NGAL measurements for predicting how a patient's CKD will progress.
To accomplish this, Michele Buemi, MD, of the University of Messina in Messina, Italy and her colleagues examined the predictive value of blood and urinary NGAL measurements for the progression of CKD in a wide variety of patients with non-advanced CKD.
The investigators evaluated the blood and urine levels of NGAL in 96 patients with non-terminal CKD who were followed for an average of 18.5 months. By the end of the study, 31 patients experienced significant progression of their disease, in some cases developing end-stage renal disease. The researchers noted that at the start of the study, these patients had increased NGAL levels compared with patients whose disease did not progress. Both urinary NGAL and blood NGAL levels each predicted worsening of CKD. Therefore, "NGAL… represents a strong and independent risk marker for progression of CKD," the authors concluded.

The findings could be used to screen patients with CKD to determine their risk of worsening disease and to indicate which patients should receive aggressive treatments. "Our study offers a great new tool for prevention of renal failure progression," said Dr. Buemi. The results are particulary important today as CKD has become a severe public health problem and incidence rates continue to rise.

CKD Treatments

Micro-Chinese Medicine Osmotherapy, it's a kind of natural herbal therapy applied externally on acupoints and all the Chinese herbal medicines used are definitely natural made.The core technology of this therapy is the micronization of effective herbals in treating kidney disease with the effective ingredients. This kind of therapy can expand blood vessels and decrease blood coagulation, thus improving blood circulation of kidneys. In addition, it can also decrease inflammatory reaction and degrade extracellular matrixes (ECM) both of which contribute to fibrosis of renal functional cells. In this way, Micro-Chinese Medicine can effectively prevent the kidneys from fibrosis and thereby stop kidney disease from progressing and have the renal function improved by repairing the damaged renal cells.

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