About 80% of children with IgA Nephropathy initiates the disease with hematuria which usually occurs after an Upper Respiratory Infection. Hematuria can exhibits in 24 to 72 hours after infection and this time hematuria can be seen by naked eyes (macroscopic hematuria). Some children are found tonsillar enlargement in this time; macroscopic hematuria may disappear after tonsillectomy.
Some children with IgA Nephropathy may manifest hematuria together with proteinuria. Their hematuria can be macroscopic or microscopic; and proteinuria usually is mild or moderate.
About 15% to 30% of children with IgA Nephropathy have Nephrotic Syndrome (massive proteinuria, Hyperlipidemia, Hypoalbuminemia and edema). These children usually do not have any infection before IgA Nephropathy attacks. Nephrotic Syndrome can put children at risk of many other diseases if it is left untreated.
Except above symptoms, children with IgA Nephropathy also can present Nephritis Syndrome (hematuria, massive proteinuria, edema and Hypertension). Hypertension usually signals exacerbation of the disease. However, only 5% of children are found of having Hypertension. Hypertension affects more adults with IgA Nephropathy than children. If people with IgA Nephropathy suffer from Hypertension, usually they have rapidly progressive kidney function deterioration. It is estimated that less than 5% of patients with IgA Nephropathy exhibit Rapidly Progressive Nephritic Syndrome.
Treatment of IgA Nephropathy
Immunotherapy is one of good choice for IgA Nephropathy. Through the treatment of promoting blood circulation to remove blood stasis,remove the immune complex and restore the inherent immune system of human body .
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