Kidney failure can affect every aspect of your body.Do you know renal failure will cause Calcium and Phosphours changes in one's body.Let us to know more knowledge about Calcium and Phosphorus changes with Renal Failure.
Renal, or kidney failure, is commonly caused by high blood pressure or
diabetes. The kidneys have many important roles,such as regulating fluid and
minerals in the body. They also signal the bone marrow to make red blood cells,
synthesize vitamin D, regulate the blood pressure, excrete waste chemicals in
the urine and regulate acid-base levels. Problems in the kidneys will affect
these capabilities and change your levels of calcium and phosphorus. The
diagnosis and management of disease should be done with the consultation of a
health-care professional.
Direction of Change
In kidney failure, the blood concentrations of calcium and phosphorus become
abnormal. Calcium levels drop, a condition called hypocalcemia, that can cause
muscle weakness and nerve problems. In contrast, phosphorus levels rise. This is
a condition called hyperphosphatemia, which can cause bone problems and
itching.
Mechanisms
Low calcium occurs in kidney failure for at least two reasons. First, in
kidney failure, the kidneys cannot synthesize vitamin D. Vitamin D normally
raises the level of calcium in the body. Without vitamin D, calcium is not
absorbed from the diet. Second, high levels of phosphate bind to calcium and can
deposit in the tissues. Phosphate, which contains phosphorus, rises because the
kidneys are normally responsible for excreting phosphate. When they do not work,
phosphate is absorbed in the diet and not excreted.
Complications
Low calcium levels encourage the release of parathyroid hormone from the
parathyroid glands in the neck. Parathyroid hormone increases blood calcium by
reabsorbing calcium from the bones. This can lead to a condition called renal
osteodystrophy. In this disease, kidney failure leads to bone loss. Low calcium
can also lead to muscle cramping. The calcium-phosphate deposits in the skin can
cause itching. Other symptoms and complications involve loss of other functions
of the kidney and the buildup of other waste products, such as urea.
Diagnosis
The diagnosis of low calcium and high phosphorus can be made on a blood test.
Renal failure is diagnosed from a history, physical exam, laboratory findings,
and possibly imaging, such as ultrasound or a biopsy, in which tissues are
removed and studied. In addition to low calcium and high phosphate, blood
studies will show other abnormalities such as a high creatinine, blood-urea
nitrogen and potassium.
Management
The management of renal failure in general involves addressing the underlying
cause, such as treating an infection or suppressing an abnormal immune response
against the kidneys. Hypocalcemia is treated with vitamin D and calcium
supplements. High phosphates are treated with a low phosphate diet and drugs
that bind to phosphate. Often, kidney failure will require dialysis, which is a
machine that acts as an artificial kidney. Dialysis is usually performed several
times per week to filter the blood and regulate the fluid and mineral
levels.
Treatments
Change the environment of your kidneys is one important factor to treat your kidney disease.Immunotherapy is one of this therapy.
It is reported that 85%-90% of kidney diseases result from inappropriate
immune response and low immunity. The reason why we human being can be free from
the attack of bacteria or virus is that we have strong immune system.
However, once our immune system is disturbed, antigens can combine antibodies
easily so as to form immune complexes. These complexes can build up in any part
of our body to cause damage via blood circulation. Kidney disease, such as IgA
Nephropathy, Lupus Nephritis and Purpura Nephritis, occurs as a consequence of
the immune complex deposition in kidney. Based on this, many kidney experts work
together to create Immunotherapy in recent years.
Immunotherapy is a great alternative treatment for kidney disease especially
which is due to autoimmune disease. As a combination of herbal medicines and
western medicines, this therapy shows outstanding therapeutic effects on not
only treating kidney disease but also regulating patients’ immune system.
Have any questions?Send me an e-mail:
kidney-treatment@hotmail.com .
