Polycystic Kidney Disease with Hematuria and High Creatinine Level

Do you want to know why PKD patients always with blood in urine?And What is the right therapy for PKD,the follwing content will tell you the answer for the question.
More than one quarter patients with Polycystic Kidney Disease (PKD) suffer from hematuria or blood in urine at the early stages of Polycystic Kidney Disease. Most of them have no ideal of PKD before hematuria occurs among them. Those cysts stress other renal tissues, destroy renal function and cause many complications which may arouse hematuria or blood in urine, such as Urinary Tract Infection and Kidney Stone.
Combined with broken cysts, there are three main reasons for hematuria or blood in urine in Polycystic Kidney Disease (PKD).
1. The broken cysts
Those cysts in kidney are covered by many capillaries on their surface. With the growth, those cysts are stretching their epithele in the state of stress. Squeezed or knocked by the external forces, they are broken as well as the capillaries. Blood can be found in urine. At the same time, this kind of hematuria is usually intermittent and combined with sharply lower back pain. What’s worse, it might cause abdominal infection and even Sepsis, so it is important for patients with PKD to avoid strenuous activities and infections.
2. Urinary Tract Infection
As those cysts grow, they will stress the renal tissues including renal tubules and capillaries, which will reduce blood volume and slow down blood flow. Accordingly, less urine are formed and the urine tends to deposit in body for a longer time, which increase the possibility of bacteria breeding and further infecting upper and lower urinary tract. Especially in upper urinary tract infection, if the glomeruli are infected and their mechanical barrier as well as charge barrier is destroyed, red cells can not be prevented passing blood vessels into urine. This kind of hematuria is continuous. Urinary Tract Infection plays an important role in damaging renal function of patients with PKD.
3. Kidney Stone
In Polycystic Kidney Disease (PKD), apart from the reasons of diets and the lack of water in body, the nucleus of condensation and obstruction of urine play important roles in the forming of Kidney Stone. The obstruction makes urine deposit longer than before. As the nucleus, Calcium or other mineral have enough time to form Kidney Stone. The movement of those stones can rub the capillaries in urinary tract and cause bleeding. This kind of Hematuria is usually companied by renal colic.
PKD Patients suffer from hematuria mainly because of the broken cysts. Several days later, it will disappear, but it can develop into continuous hematuria when Polycystic Kidney Disease deteriorates.

Treatments

Do you heard Micro-Chinese Medicine Osmotherapy?This therapy is based on Chinese herb.In other hand this therapy in virtue of a western machine.This machine will make the Chinese herbs take affect directly in kidneys.Through Chinese herbs Creatinine level will also be removed naturally.

Have any questions?Consult me through kidney-treatment@hotmail.com .

 

Blood And Protein in urine and Chronic Kidney Disease Progression

Hematuresis and Protein in urine are the common symptoms in CKD. Do you know these symptoms can predicts the CKD Progression.The following content will show you the knowledge about this.

measuring a small protein in the blood and urine can predict which patients with non-advanced chronic kidney disease (CKD) will progress to a more serious form of the disease, according to a new study. The findings could be used to devise a new screening method for identifying which patients should receive aggressive therapies to prevent the progression of their disease.
The blood and urine of some individuals with impaired kidney function have increased levels of a small protein called Neutrophil Gelatinase-Associated Lipocalin (NGAL). NGAL is released from injured renal tubular cells, which are cells crucial for proper functioning of the kidneys. Preliminary research has also shown that individuals with high levels of NGAL experience worsening of their kidney function within one year, compared with individuals with lower levels of NGAL. However, no definitive study has demonstrated the potential of NGAL measurements for predicting how a patient's CKD will progress.
To accomplish this, Michele Buemi, MD, of the University of Messina in Messina, Italy and her colleagues examined the predictive value of blood and urinary NGAL measurements for the progression of CKD in a wide variety of patients with non-advanced CKD.
The investigators evaluated the blood and urine levels of NGAL in 96 patients with non-terminal CKD who were followed for an average of 18.5 months. By the end of the study, 31 patients experienced significant progression of their disease, in some cases developing end-stage renal disease. The researchers noted that at the start of the study, these patients had increased NGAL levels compared with patients whose disease did not progress. Both urinary NGAL and blood NGAL levels each predicted worsening of CKD. Therefore, "NGAL… represents a strong and independent risk marker for progression of CKD," the authors concluded.

The findings could be used to screen patients with CKD to determine their risk of worsening disease and to indicate which patients should receive aggressive treatments. "Our study offers a great new tool for prevention of renal failure progression," said Dr. Buemi. The results are particulary important today as CKD has become a severe public health problem and incidence rates continue to rise.

CKD Treatments

Micro-Chinese Medicine Osmotherapy, it's a kind of natural herbal therapy applied externally on acupoints and all the Chinese herbal medicines used are definitely natural made.The core technology of this therapy is the micronization of effective herbals in treating kidney disease with the effective ingredients. This kind of therapy can expand blood vessels and decrease blood coagulation, thus improving blood circulation of kidneys. In addition, it can also decrease inflammatory reaction and degrade extracellular matrixes (ECM) both of which contribute to fibrosis of renal functional cells. In this way, Micro-Chinese Medicine can effectively prevent the kidneys from fibrosis and thereby stop kidney disease from progressing and have the renal function improved by repairing the damaged renal cells.

Have any other question?Consult me through kidney-treatment@hotmail.com .

Stages 3 and 4 Chronic Kidney Disease with Diabetes in the older people

If one person suffering from Diabetes for a long time,therre will be damaged one's kidneys.If you don't adopt the right treatment.Diabetes may be lead to kidney Failure.

Dedicated European and US clinical guidelines for type 2 diabetes in the elderly have been released, but they do not specifically address the issue of advanced chronic kidney disease (CKD) in older patients with diabetes. General clinical guidelines have been published on the treatment of patients with diabetic nephropathy (DN), but these address the issue of how to prevent progression and treat advanced DN without distinguishing between different age groups. Elderly patients with diabetes and stages 3 to 4 CKD have particular needs that differ from those of younger patients with the same conditions. This is mainly due to their frailty and shorter life expectancy. Differently tailored therapeutic strategies are needed, which may have less stringent targets; and the use of common drugs should be critically evaluated. The management agenda (metabolic control, low-protein diet, controlling BP, preventing progression of advanced DN, preventing cardiovascular outcomes) for these patients is discussed in light of the limits and perspectives of current guidelines. Intensive, simultaneous management of all items on the agenda may not be feasible for a proportion of older patients, and clinicians may have to give priority to reducing some risk factors rather than others, choosing between different therapies.
In 2004, the European Diabetes Working Party for Older People launched its “Clinical Guidelines for Type 2 Diabetes Mellitus” specifically dedicated to the elderly (the European Diabetes & Aging Guidelines for short [EDAG]) (1). Guidelines for Improving the Care of the Older Persons with Diabetes Mellitus were also developed in the United States in 2003 (American Diabetes & Aging Guidelines for short [ADAG]) (2). There is a dual rationale behind guidelines specifically dedicated to the elderly. First, older people with diabetes have special needs. Second, with the demographic changes occurring in Western populations, the number of elderly individuals with diabetes is expanding dramatically. These people's life expectancy is considerably reduced: Whereas a 74-yr-old Western man without diabetes has an average life expectancy of approximately 10 yr and a woman of approximately 12 yr, when they have diabetes, their life expectancy is roughly 4 and 6 yr shorter for men and women, respectively (3).
Demographic changes in Western populations also have a significant impact on renal care. In many Western countries, the elderly now represent the most rapidly growing population initiating dialysis. In the United States, the median age of the incident population starting renal replacement therapy reached 64.6 yr in 2005, and the incidence of ESRD by age >75 yr was approximately 1500 pmp, 750 in Canada, and 500 in Italy (4). Because the prevalence of diabetes has been increasing among the elderly, it is hardly surprising that elderly individuals with diabetes contribute substantially to the overall burden of stage 5 chronic kidney disease (CKD) in Western countries. In 2005, in fact, one third of the incident cases of ESRD in the United States in people who were older than 75 yr had diabetic kidney disease (4).
Two very recently released publications are also of interest in the present contention, the Kidney Disease Outcomes Quality Initiative (KDOQI) Clinical Practice Guidelines and Clinical Practice Recommendations for Diabetes and Chronic Kidney Disease (5) and the Quality Indicators for the Care of Vulnerable Elders (the Assessing Care of Vulnerable Elders 3 [ACOVE-3] initiative) (6). Only the former marginally addresses the issue that elderly people with diabetes and CKD warrant special treatment considerations, but neither of them nor the EDAG and ADAG specifically addresses the topic of advanced CKD in older patients with diabetes. This review aims to make up for this shortcoming relating to the treatment of elderly people with diabetes and advanced renal impairment (i.e., in stages 3 and 4 CKD). As the lower age limit, we consider patients between 70 and 80 yr because such long-lasting patients with diabetes are most likely to have a considerably reduced life expectancy and a number of diabetes-related comorbidities. The relevant clinical issue here, however, is the patients’ vulnerability, not their age, so our considerations could also be extended to younger, frail patients with diabetes and stages 3 to 4 CKD.

An attempt has been made to quote and grade the level of evidence. There is a sizable amount of good-quality research on the prevention and management of the complications of type 2 diabetes and related aspects, but most of it is not specific to elderly patients, and none of these studies concerned elderly people with advanced CKD. Most of the suggestions have consequently been classified simply as clinical practice recommendations (CPR), at the level of “opinion-based” advice, whereas a clinical practice guideline (CPG) has been proposed in just one case.

Treatments of CKD

In early stage of CKD you can use Chinese Medicine to control the development of kidney disease. If you has entered stage 3 or 4 stage of kidney disease.You can use some special treatment.Do you heard Micro-Chinese Medicine Osmotherapy.This therapy make the Traditional Chinese Medicine enter your kidneys through your skin directly.So the Chinese Medicine can quickly take affect.

If you also have other questions about your kidney Disease,or if you want to know therapy about CKD.Contact me through kidney-treatment@hotmail.com .

Causes of Renal Parenchymal Disease

Do you want to know What is Renal Parenchymal Disease and What kind of kidney disease can cause renal parenchymal disease? Follow the folling content and learn more about Renal Parenchymal Disease,
Renal parenchymal disease includes maladies that damage the outermost internal region of the kidney where filtration and urine formation occur. Autoimmune disorders, medical conditions, or obstructions may all contribute to this disease. Lupus, bacterial infections,diabetes and high blood pressure, along with kidney stones can traumatize delicate tissue, causing scarring and possibly leading to eventual kidney failure. Managing systemic diseaseprocesses, however, may prevent kidney damage and failure from occurring.
Millions of nephrons lie within the renal parenchymal area of each kidney. The nephrons contain arterioles, or small blood vessels, known as glomeruli, that are surrounded by tubules. The glomeruli receive oxygen rich blood that contain excess electrolytes, salts, and water and transport the unnecessary blood products and water to the renal tubules. The tubules pass through the renal medulla, or the center of the kidney, into another system of tubules that combine and empty into the ureter.

Studies estimate that up to 50% of patients diagnosed with lupus erythematosus experience arenal parenchymal disease known as lupus nephritis. Lupus causes abnormal antibody production in the body, and these malfunctioning antibodies attack healthy cells, including those within the nephrons. The kidney's normal filtering processes are diminished when cell damage in the parenchymal tissue occurs. The disease might also produce inflammation of the kidney, adding pressure to damaged glomeruli.

Symptoms of lupus nephritis include swelling in the feet, legs, and around the eyes. Patients may excrete urine that appears foamy or bloody. Inadequate filtering and excess fluid also cause increased blood pressure. Blood tests evaluate the efficiency of the filtering process andultrasound imaging reveals abnormal kidney tissue. Treatment may include glucocorticoids and chemotherapeutic agents to reduce overall inflammation.
Uncontrolled diabetes may eventually lead to renal parenchymal disease and subsequent kidney failure. The flood of sugar-laden blood in the glomeruli puts increased stress on the filtering system and increases pressure within the delicate arterioles. The strain of continuously ridding the body of sugar diminishes filtering ability and eventually causes permanent damage. Protein spills into the urine instead of staying in the blood and sugar also enters the urine. Renal insufficiency contributes to hypertension, but hypertension can also cause renal problems.
Excess body fluids trigger renin/angiotensin release and subsequent response from the sympathetic nervous system to constrict blood vessels, forcing more blood to the kidneys.Renal parenchymal disease takes place when this constriction forces fluid through fragile glomeruli and other capillaries, causing cellular damage to vessel linings. During the reparative process, scarring occurs, and vessels become thickened and stiff. Without a permeable surface, glomeruli filtration is diminished.

Cellular and tissue damage can also occur when an patient has kidney stones. Uric acid andcalcium crystals combine with oxalate to form stones of various sizes and shapes. Bacterial infections initiate increased enzyme, ammonia, and other chemical production, which may produce a by-product known as struvite stones. Besides inflammation and swelling, which contribute to decreased filtration, the foreign objects may tear vessels and tissues. Scar tissueforms, inhibiting proper kidney function and contributing to renal parenchymal disease.

Treatments of Renal Parenchymal Disease 

Do you heard Blood Pollution Therapy? Today's research finding that Polluted Blood is the root cause of kidney disease.And this therapy can cleared the Polluted Blood .

If you want to know more about this therapy,or you have any questions want to ask about your kidney problem.Contact me through kidney-treatment@hotmail.com .

What is the relationship between diabetes and creatinine level?

Do you want to know how does diabetes lead to high creatinine level? And Do you want to know the relationship between diabetes and high creatinine level?
My mother was diagnosed with kidney problem and infection in her urine/blood. A nephrologist cleared out the infection she had but by that time her creatinine level had gone up to 8. The doctor prescribed Endoxin and Wysolone medication. After that her haemoglobin and white cells went beyond the range. In 2 subsequent visits doctor checked her creatinine which was found to be 4.9 & 5. Her sugar was found to be 536 and the doctor said that this was because of Wysolone hence he reduced the dose from 25 to 15 mg. After that her sugar levels came down to 430. Recently the doctor advised her to take insulin with 4,4,4 units daily (3 times) to maintain her sugar levels & asked her to go on a strict diet. When we measured it after 3 days after stating insulin, her sugar level came down to 230. We consulted our doctor so he increased the insulin dose as 6,4,4. Her creatinine level still varies between 4.5 to 4.9. I need your opinion about the same. Can her creatinine & glucose levels come down to normal in future with the current medication & diet? Will she face any other problem/complications in future and what precautions should we take to avoid further complications? My mother is 56 years old and weighs 66kgs. She has high blood pressure since 10 years and is taking ATANOL-50.

Issues to be addressed in query are 1) Wysolone (steroid) induced Diabetes mellitus and 2) DM and raised creatinine levels (kidney failure).
There is a relationship which exists between Diabetes Mellitus and raised creatinine levels. Usually this situation arises when DM is there for a long time and not controlled and this situation is called as diabetic nephropathy meaning kidney disease due to DM. Initially this presents as protein in urine but as the disease progresses creatinine level goes up. This type of kidney failure is irreversible and these patients need dialysis and renal transplant.

In your mothers case high creatinine levels are not due to DM but seems to be due to glomerulonephritis which can be treated. Best person for this is a nephrologist. In this case the blood sugars are high because of wysolone and hopefully blood sugars should come down when wysolone is tapered off. But with such a high levels of sugar your mother needs higher doses of insulin i.e., at least 10 units of Actrapid/Huminsulin R 30 minutes before meals three times a day and Insulatard/ Lente 10 units at bed time. Home monitoring of blood glucose is also needed. For control of blood sugars please get in touch with an endocrinologist or daibetologist or provide us more details so that we can advise you accordingly.

How to lower high creatinine level naturally?

In order to treat high creatinine level in diabetes,we need to take measures in diet perspective and treatment perspective.
Diet Plan
Have less meat.Meat is the resource of creatinine.Therefore heavy burden can be relieved day by day.
Have a low-sodium diet and kidney functions can be protected timely and immediately.
Kidney Treatment


Micro-Chinese Medicine Osmotherapy is a good choice to lower your high creatinine level.This therapy combined Chinese herbs and Modern Machine.In other word,this therapy combined Traditional Chinese Medicine and Western Medicine.So this is a Innovation in kidney disease treatment.

Do you want to know more about this therapy.Contact me through kidney-treatment@hotmail.com .

The introduction of Renal Fibrosis

The suitable is essential If you are stay in Renal Fibrosis.Because with the development of this disease.The treatment will become difficult.
Renal fibrosis is a pathological change as well as physiological change. Renal fibrosis is a gradual process whose development starts from healthy kidney function, to impaired kidney function, damaged kidney function finally to complete loss of kidney function.
As results of trauma, infection, inflammation, blood circulation disorder, immune reaction and other pathological factors, the intrinsic cells of kidney are damaged. When it approaches to the end stage kidney disease (ESRD), large amount of collagen deposition will trigger gradual sclerosis of the kidney. In this case, bruises will appear to affect the kidney function till the kidney function is completely lost. The process of the sclerosis of renal cells is known as renal fibrosis which features the abnormal deposition in the ECM.
First stage:
This stage is called inflammatory reaction stage in which various kidney tissues starts to get damaged. In this stage, there is no symptoms and disorders for patient other than some abnormal results in Urine Analysis, as a result this is stage is also known as symptoms-free stage. As the glomerulus have strong compensative function, the kidney function is this stage may not be affected or show minor disorder. However the pathological damages to the kidney is really serious, some of the patient may have got glomerular sclerosis and the kidney damage is always prior to the appearance of symptoms. If proper treatment is applied in such stage, such as enlargement of blood vessel, anti inflammation, anti freezing and protection against thrombus, the condition is still reversible or could be even cured. If the patient missed the best treatment period, the pathological damages in the kidney will be worsened and the condition will develop into the stage of formation of renal fibrosis in which the treatment would be very difficult to carry out and the effective of which will be limited.
Second stage:
This stage is known as the formation period of renal fibrosis. In this stage, the formation of renal fibrosis will damage the renal cells so as the kidney function. The condition will develop into decompensative period or renal failure period. If the abovementioned measures are applied timely in this stage, the treatment is still likely to have a reversible effect on the patient to avoid dialysis. If not, together with some other unfavorable factors, the condition may develop into the stage of bruises stage---the end-stage kidney disease.
The last stage:
Once the renal fibrosis transforms to bruises tissue, it becomes incurable and irreversible. If the patient still possesses more than 1L of urine per day, it means there is still certain amount kidney function left for the patient. With the help of micro-herbal Chinese medicines therapy, the remaining kidney function could be protected and stopped from further worsening. Then it will be hopeful for patient reduce the frequency of dialysis or even get rid of dialysis.

Treatments

Different from the previous kidney treatment, blood pollution therapy focuses on treating patients’ polluted blood before reversing their kidney damage. As a great breakthrough for treating various kidney disease in this year, this therapy shows dramatically therapeutic effect.

Have any questions?Contact me through kidney-treatment@hotmail.com .

The causes and Treatments of Hematuria in PKD patients

Blood in urine is one of common symptoms for PKD patients.Do you want to know the causes and treatments of Hematuria in PKD patients.

Causes of Hematuria in PKD Patients

1. Infection
Cysts in kidneys are always filled with yellow cystic fluids and they can cause hydrops in kidneys. With hydrops in kidneys, infection occurs more easily, which is also a cause of blood in urine for Polycystic Kidney Disease patients. The most common for kidney disease is the repeated urinary tract infection.
2. Cyst rupture
The most likely cause is cyst rupture. With the continuous enlargement of kidney cysts, they tend to break up and cause bleeding, especially then the cysts are larger than 4cm. You may experience the repeated rupture in the renal failure stage, since the cysts are very big at that condition. If cyst rupture is seriously, your doctor has to take operations to cleanse away the blood and cyst fluid in your internal cavity in case that it throws you into emergency.
3. Inability of glomeruli
Glomeruli are the small functional unites in the kidneys. Glomeruli filter the all blood in the body. They eliminate the toxins and hold the essential substance, including blood cells and protein, as well as minerals etc. If cysts pressure forces to glomeruli constantly, the small renal unites fail to function well, leaking the blood cells into urine.
4. Kidney stone
Many patients appear to have kidney stones after diagnosis of the cystic kidney disease. Kidney stones can rub the capillaries urinary tract and cause bleeding. Many herbs are suggested to dissolve the stones and cleanse away them naturally.

Treatments of blood in urine in PKD patients

Micro-Chinese Medicine Osmotherapy

Chinese Herbals have a long history for treating kidney disease.Traditionally speaking,chinese herbals removes stasis which is totally different from Western medicines.More specifically,most western medicines have no function of helping our body to remove stasis including creatinine out of the body.Micro-Chinese Medicine Osmotherapy is based on Chinese herbals,which treats polycystic kidney disease from root perspective.The activated Chinese medicines in Micro-Chinese Medicine Osmotherapy shrink cysts and oppress cysts growth.It shrinks cysts by changing the pressure of internal and external.Meanwhile the activated Chinese medicines destroy cyst’s structure thus oppressing cysts growth.

Do you have any other questions? You can send an email to the experts in kidney-treatment@hotmail.com .